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Simvastatin, a synthetic analog of lovastatin, is a specific inhibitor (statin) of HMG-CoA reductase the rate-controlling enzyme of the mevalonate pathway that

Biological Significance, is a hypolipidemic drug used to control elevated cholesterol, or hypercholesterolemia. is a member of the statin
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After 18 days of treatment with in dogs at a dose of 8 mg/kg/day, plasma cholesterol levels were reduced by 33%. also suppresses TNF-
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| C25H38O5 | CID 54454 – structure, chemical names, physical and It is a white, nonhygroscopic, crystalline that is practically insoluble in
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